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In another study in normal volunteers, concomitant administration of buspirone and haloperidol resulted in increased serum haloperidol concentrations. The clinical significance of this finding is not clear.

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For buspirone, the following should be co nsidered:

Allergies¡XTell your doctor if you have ever had any unusual or allergic reaction to buspirone. Also tell your health care professional if you are allergic to any other substances, uch as foods, preservatives, or dyes.

Adverse Effects

Autonomic:
Dry mouth, sweating/clamminess, blurred vision, constipation. Infrequently, urinary frequency, retention and burning, flushing.
Cardiovascular:
Tachycardia, chest pain, palpita tions. Infrequently, syncope, hypotension, hypertension. Rarely, congestive heart failure, cerebrovascular accident, myocardial infarction, cardiomyopathy, bradycardia, EKG change.
Gastrointestin al:
Nausea, gastrointestinal distress, diarrhea, vomiting. Infrequently, flatulence, increased appetite, anorexia, hypersalivation, rectal bleeding, irritable colon. Rarely, burning tongue.
Re spiratory:
Nasal congestion. Infrequently, shortness of breath, chest congestion, difficulty breathing, hyperventilation. Rarely, epistaxis.

What side effects may occur?

More common side effects may include:
- Dizziness, dry mouth, fatigue, headache, light-headedness, nausea, nervousness, unusual excitement

Less common or rare side effects may include:
- Anger/hostility, blurred vision, bone aches/pain, confusion, constipation, decreased concentration, depression, diarrhea, fast, fluttery heartbeat, incoordination, muscle pain/aches, numbness, pain or weakness in hands or feet, rapid heartbeat, rash, restlessness, stomach and abdominal upset, sweating/clamminess, tingling or pins and needles, tremor, urinary incontinence, vomiting, weakness

How should this medicine be used?

Take BuSpar exactly as prescribed. Do not be discouraged if you feel no immediate effect. The full benefit of this drug may not be seen for 1 to 2 weeks after you start to take it.

What Is It

Buspirone (byoo-SPYE-rone) is used to treat certain anxiety disorders or to relieve the symptoms of anxiety. However, buspirone usually is not used for anxiety or tension caused by the stress of every day life.

It is not known exactly how buspirone works to relieve the symptoms of anxiety. Buspirone is thought to work by decreasing the amount and actions of a chemical known as serotonin in certain parts of the brain.


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