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Other Medicines

If Nexium is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nexium with the foll owing:

- Diazepam (Valium)
- Digoxin (Lanoxin)
- Iron salts (Ferro-Sequels)
- Ketoconazole (Nizoral)
- Warfarin (Coumadin)

There's no problem, however, with com bining antacids and Nexium; no unwanted interaction will result.

What side effects may occur?

Rare side effects may include:
- Abnormal sense of smell, acne, allergic reaction, anemia, apathy, back pain, black stools, blood disorders, blood in urine, burping, change in bowel habits, chest pain, chills, confusion, constipation, coughing, cramps, difficulty breathing, difficulty swallowing, dizziness, dry mouth, ear infection, earache, enlarged abdomen, enlarged thyroid gland, eye infec tion, facial swelling, fast or irregular heartbeat, fatigue, fever, flu-like symptoms, flushing, frequent or increased urination, fungal infections, general feeling of illness, hernia, hiccups, high b lood pressure, hives, hot flushes, impotence, inability to sleep, increased appetite, indigestion,

How should this medicine be used?

Nexium comes as delayed-release (long-acting) capsule to take by mouth. For inflamed esophagus and other conditions in which the stomach makes too much acid, one capsule is usually taken once a day fo r 4 to 8 weeks. It may be used for up to 6 months after your symptoms have improved.

For ulcers, one capsule is usually taken in combination with antibiotics once a day for 10 days.

Nexium should be swallowed whole and taken at least 1 hour before meals. Nexium may be taken with water, orange juice, apple juice, or yogurt.

Other medical problems

Before using Nexium,

- tell your doctor and pharmacist if you are allergic to Nexium, omeprazole (Prilosec), lansoprazole (Prevacid), or any other drugs.
- tell your doctor and pharmacis t what prescription and nonprescription medications you are taking, especially iron supplements or vitamins that contain iron, ketoconazole (Nizoral), digoxin (Lanoxin), and herbal products.
- te ll your doctor if you have or have ever had liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using Nexium, call your doctor immediately.

What Is It

Nexium is in a class of drugs called proton pump inhibitors. It works by decreasing the amount of acid made in your stomach. Nexium is used to treat your esophagus, the area between your throat and st omach that has become irritated, painful, and swollen from too much acid in your stomach.

It is used to treat heartburn, acid indigestion, sour stomach, and other conditions in which the stom ach makes too much acid. Nexium also is used in combination with antibiotics to treat ulcers.

Overdosage

Any medication taken in excess can have serious consequences. There have been some reports of Nexium overdoses. If you suspect an overdose, seek medical attention immediately.

Symptoms of Ne xium overdose may include:
- Blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating


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